The Best Nightlife Spots in St. Louis, Missouri

Explore the best nightlife spots in St. Louis with 10Best's carefully selected list of clubs, bars, restaurants, music venues, stores & more.

The Best Nightlife Spots in St. Louis, Missouri

St. Louis is a vibrant city with plenty of nightlife options to choose from. From the bustling Washington Avenue to the historic Central West End, there are plenty of places to explore and enjoy. South Grand offers a unique mix of ethnic restaurants, shops, and bars, while The Loop and Delmar Boulevard provide a lively atmosphere with music, clubs, and coffee shops.

And don't forget the city center, which is home to some of the most exclusive places in the region. Of all the clubs and bars in St. Louis, 10Best has narrowed down the options to the places with the most attractive and best reputation. If you're looking for a great night out in St. Louis, here are ten of the best spots to check out:

Washington Avenue

Washington Avenue is located in the heart of St.

Louis and is full of restaurants, bars, music venues, and nearby clubs and casinos. Some of the popular clubs on Washington Avenue include The Boom Boom Room, Club Amnesia, and Europe Club.

Central West End

The Central West End is a great place to take it easy and enjoy some delicious food and drinks. Bar Italia, Drunken Fish, Culpepper Grill & Bar are just a few of the many restaurants located here. There's also a large illuminated water fountain that makes for a great photo opportunity.

South Grand

South Grand is full of flavor and offers plenty of nearby restaurants and parks for strolling around.

The Upstairs Lounge and The Gin Room are two popular bars in this area.

The Loop & Delmar Boulevard

The Loop and Delmar Boulevard are two of the best places to have fun late at night. There are plenty of ethnic restaurants and bars here as well as unique stores, tattoos parlors, piercings shops, music venues, clubs, and coffee shops.

City Center

The city center is a beautiful nightlife district in St. Louis that you won't want to miss when you go out at night. In addition to its many clubs and bars, this neighborhood is home to some of the city's most beautiful attractions and places of interest.